| Trial Name | Description |
| Window of Opportunity |
Dr. Anthony Nichols A Window of Opportunity Study to Assess the Modulation of Biomarkers in Head and Neck Squamous Cell Cancer (HNSCC) By Preoperative Treatment with BYL719. |
| RADIO |
Dr. Sara Kuruvilla Randomized Trial Comparing Low-Dose Weekly to High-Dose Cisplatin Concurrent with Radiation for Locally Advanced Head and Neck Cancer. |
| LIBRETTO HN |
Dr. E. Winquist A Multicenter, Randomized, Open-label, Phase 3 Trial Comparing Selpercatinib to Physicians Choice of Cabozantinib or Vandetanib in Patients with Progressive, Advanced, Kinase Inhibitor Naive, RET-Mutant Medullary Thyroid Cancer |
| Dab+Tram Thyroid |
Dr. E. Winquist A randomized, double-blind, placebo-controlled Phase III study to evaluate the efficacy and safety of dabrafenib plus trametinib in previously treated patients with locally advanced or metastatic, radio-active iodine refractory BRAFV600E mu |
| PRESERVE |
Dr. David Palma Preservation of Swallowing in Resected Oral Cavity Squamous Cell Carcinoma: Examining Radiation Volume Effects (PRESERVE): A Randomized Trial. |
| CE.7 |
Dr. Melody Qu A Phase III Trial of Stereotactic Radiosurgery Compared with Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5-15 Brain Metastases. |
| HNC.2 |
Dr. Eric Winquist Randomized Phase II/III Trial of Radiotherapy with Concurrent MEDI4736 (Durvalumab) vs. Radiotherapy with Concurrent Cetuximab in Patients with Locoregionally Advanced Head and Neck Cancer with a Contraindication to Cisplatin. |
| ASPEN-03 HN |
Dr. E. Winquist A Phase 2 Study of ALX148 in Combination with Pembrolizumab in Patients with Advanced Head and Neck Squamous Cell Carcinoma (ASPEN-03) |
| HN.11 H&N |
Dr. Danielle Macneil Not Yet Open - SPECT-CT Guided Elective Contralateral Neck Treatment (SELECT) for Patients with Lateralized Oropharyngeal Cancer: A Phase III Randomized Controlled Trial. |
| eVOLVE-HNSCC |
Dr. Sara Kuruvilla Not Yet Open - A Phase III, Randomized, Open-Label, Multi-Center, Global Study of Volrustomig (MEDI5752) as Sequential Therapy Versus Observation in Participants with Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma, Who Have Not Progress |
| 5FAST HN |
Dr. Chris Goodman Not Yet Open - "3-5 FrAction Stereotactic Body Radiation Therapy for Palliation of Head and Neck Squamous Cell Carcinoma: the FAST Phase II Randomized Trial" |